Degraded Hyaluronic Acid-Modified Magnetic Nanoparticles

Hydrodynamic characterisation of chemically degraded hyaluronic acid

Hyaluronic acid (HA) is a natural macromolecule with importance in the pharmaceutical, medical and cosmetic industries. The knowledge of its hydrodynamic properties is fundamentally important for further study on its applications. The aim of our study was to investigate and provide hydrodynamic parameters for six different molar mass samples chemically produced by depolymerisation of a high mol...

Lubrication Of Degraded Cartilage By Hyaluronic Acid

LSMO Nanoparticles Coated by Hyaluronic Acid for Magnetic Hyperthermia

Magnetic hyperthermia with the treating temperature range of 41-46 °C is an alternative therapy for cancer treatment. In this article, lanthanum strontium manganates (La1-x Sr x MnO3, 0.25 ≤ × ≤ 0.35) magnetic nanoparticles coated by hyaluronic acid (HA) which possesses the ability of targeting tumor cells were prepared by a simple hydrothermal method combined with a high-energy ball milling te...

Hyaluronic Acid-Modified Magnetic Iron Oxide Nanoparticles for MR Imaging of Surgically Induced Endometriosis Model in Rats

Endometriosis is defined as the presence of endometrial tissue outside the uterine, which may affect nearly 60% of women in reproductive age. Deep infiltrating endometriosis (DIE) defined as an endometriotic lesion penetrating into the retroperitoneal space or the wall of the pelvic organs to a depth of at least 5 mm represents the most diagnostic challenge. Herein, we reported the use of hyalu...

Biomedical Application of Hyaluronic Acid Nanoparticles

Hyaluronic acid (HA) is a naturally occurring biodegradable polymer with a variety of applications in medicine including tissue engineering, dermatological fillers, and viscosupplementation for osteoarthritis treatment. The cytotoxicity of crosslinking techniques for scaffold fabrication and the high viscosity of viscosupplements have been issues impeding the development of products from HA. Th...